Colorectal cancer, the third most common cancer, is a highly heterogeneous disease at both molecular and morphological levels. Its progression is shaped by complex interactions between tumor cells and the surrounding stromal and immune cells. Our research group focuses on three key areas: (1) identifying the factors that drive colorectal cancer heterogeneity, (2) uncovering the role of tumor-host interactions in disease progression, and (3) developing novel biomarkers to advance precision medicine.

As a doctoral researcher in our group, you will participate in the analysis of large colorectal cancer cohorts. You will apply techniques such as multiplex immunohistochemistry, in situ hybridization, spatial transcriptomics to uncover the molecular variations that drive tumor phenotypes in colorectal cancer. You will apply data analysis methods and bioinformatics analyses to analyze large-scale molecular data. The findings of the project could refine future tumor classification systems, aid in developing novel biomarkers, and enable more personalized treatment approaches.

The doctoral training will give you a strong background for future tissue-based research related to cancer biology, tumor immunology, and bioinformatics. It will offer rich opportunities for networking, mobility, and further career development after completing the PhD in three years. 

Qualifications 

• Master’s or equivalent degree (e.g. licentiate) in biochemistry, biomedicine, bioinformatics, cell biology, data analysis, genetics, medicine, molecular biology, molecular genetics, or related fields
• Strong motivation to learn and apply new research methods relevant to the project. Excellent communication and teamwork skills. Fluent in written and spoken English